Letting this effect run out will result in 100 adventures of Goofball Withdrawal after rollover. However, it should be noted that taking the goofballs without letting the effect run out on the same day will prevent Goofball Withdrawal.
References
In modern popular culture, the terms "goofballs" and "hopped up on goofballs" refer to various types of drugs and their effects. Originally (circa 1970s) the term "goofballs" referred to quaaludes. Recently, the term has become very ambiguously defined and can refer to anything from simple benzodiazepine (a class of mild sedatives) intoxication to a combination of cocaine or amphetamines and barbiturates.